KCNA7 Antibody

Datasheet
Code CSB-PA847218LA01HU
Size US$299
Uniprot No. Q96RP8
Image
  • IHC image of CSB-PA847218LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunogen Recombinant Human Potassium voltage-gated channel subfamily A member 7 protein (1-143AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Potassium voltage-gated channel subfamily A member 7 (Voltage-gated potassium channel subunit Kv1.7), KCNA7
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Neuroscience
Target Names KCNA7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity).
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.7/KCNA7 sub-subfamily
Tissue Specificity Highly expressed in skeletal muscle, heart and kidney.
Database Links

HGNC: 6226

OMIM: 176268

KEGG: hsa:3743

STRING: 9606.ENSP00000221444

UniGene: Hs.306973

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