KCND1 Antibody

Datasheet

Code	CSB-PA012022LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012022LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA012022LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA012022LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KCND1 Polyclonal antibody

Uniprot No.

Q9NSA2

Target Names

KCND1

Alternative Names

Kcnd1 antibody; KCND1_HUMAN antibody; Kv4.1 antibody; mShal antibody; OTTHUMP00000025805 antibody; OTTHUMP00000025806 antibody; Potassium voltage gated channel Shal related subfamily member 1 antibody; Potassium voltage gated channel subfamily D member 1 antibody; Potassium voltage-gated channel subfamily D member 1 antibody; Shal type potassium channel antibody; Voltage gated potassium channel Kv4.1 antibody; Voltage gated potassium channel subunit Kv4.1 antibody; Voltage-gated potassium channel subunit Kv4.1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Potassium voltage-gated channel subfamily D member 1 protein (410-647AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KCND1 Antibody (Product code: CSB-PA012022LA01HU) is Non-conjugated. For KCND1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA012022LB01HU	KCND1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012022LC01HU	KCND1 Antibody, FITC conjugated
Biotin	CSB-PA012022LD01HU	KCND1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.

Gene References into Functions

S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation. PMID: 24675763
reflected in the immunoblotting data KV4.1 receptors were detected at higher levels of expression in patient with cortical dysplasia with intractable epilepsy. PMID: 25003238
These results demonstrated that Kv4.1 plays a role in proliferation of tumorigenic human mammary epithelial cells. PMID: 19401188

Subcellular Location

Membrane; Multi-pass membrane protein. Cell projection, dendrite.

Protein Families

Potassium channel family, D (Shal) (TC 1.A.1.2) subfamily, Kv4.1/KCND1 sub-subfamily

Tissue Specificity

Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain.

Database Links

HGNC: 6237

OMIM: 300281

KEGG: hsa:3750

STRING: 9606.ENSP00000218176

UniGene: Hs.55276

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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