KCND1 Antibody

Code CSB-PA012022LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012022LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA012022LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA012022LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KCND1 Polyclonal antibody
Uniprot No.
Target Names
KCND1
Alternative Names
Kcnd1 antibody; KCND1_HUMAN antibody; Kv4.1 antibody; mShal antibody; OTTHUMP00000025805 antibody; OTTHUMP00000025806 antibody; Potassium voltage gated channel Shal related subfamily member 1 antibody; Potassium voltage gated channel subfamily D member 1 antibody; Potassium voltage-gated channel subfamily D member 1 antibody; Shal type potassium channel antibody; Voltage gated potassium channel Kv4.1 antibody; Voltage gated potassium channel subunit Kv4.1 antibody; Voltage-gated potassium channel subunit Kv4.1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Potassium voltage-gated channel subfamily D member 1 protein (410-647AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The KCND1 Antibody (Product code: CSB-PA012022LA01HU) is Non-conjugated. For KCND1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA012022LB01HU KCND1 Antibody, HRP conjugated ELISA
FITC CSB-PA012022LC01HU KCND1 Antibody, FITC conjugated
Biotin CSB-PA012022LD01HU KCND1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
Gene References into Functions
  1. S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation. PMID: 24675763
  2. reflected in the immunoblotting data KV4.1 receptors were detected at higher levels of expression in patient with cortical dysplasia with intractable epilepsy. PMID: 25003238
  3. These results demonstrated that Kv4.1 plays a role in proliferation of tumorigenic human mammary epithelial cells. PMID: 19401188
Subcellular Location
Membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein Families
Potassium channel family, D (Shal) (TC 1.A.1.2) subfamily, Kv4.1/KCND1 sub-subfamily
Tissue Specificity
Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain.
Database Links

HGNC: 6237

OMIM: 300281

KEGG: hsa:3750

STRING: 9606.ENSP00000218176

UniGene: Hs.55276

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