KCTD1 Antibody, HRP conjugated

Code CSB-PA744477LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KCTD1 Polyclonal antibody
Uniprot No.
Target Names
KCTD1
Alternative Names
KCTD1 antibody; C18orf5 antibody; BTB/POZ domain-containing protein KCTD1 antibody; Potassium channel tetramerization domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human BTB/POZ domain-containing protein KCTD1 protein (1-257AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
Gene References into Functions
  1. results reveal a novel role for Cu(2+) in determining the structure and function of KCTD1 PMID: 27596723
  2. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding. PMID: 26334369
  3. KCTD1 functions as a novel inhibitor of Wnt signaling p PMID: 24736394
  4. Mutations in KCTD1 cause scalp-ear-nipple syndrome. PMID: 23541344
  5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  6. indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 family, especially for AP-2alpha PMID: 19115315

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Involvement in disease
Scalp-ear-nipple syndrome (SENS)
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in mammary gland, kidney, brain and ovary.
Database Links

HGNC: 18249

OMIM: 181270

KEGG: hsa:284252

STRING: 9606.ENSP00000408405

UniGene: Hs.526630

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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