KIAA0319L Antibody, Biotin conjugated

Code CSB-PA816919LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KIAA0319L Polyclonal antibody
Uniprot No.
Target Names
KIAA0319L
Alternative Names
Dyslexia-associated protein KIAA0319-like protein antibody; K319L_HUMAN antibody; KIAA0319 like antibody; KIAA0319L antibody; KIAA1837 antibody; PKD1 like antibody; Polycystic kidney disease 1 like antibody; Polycystic kidney disease 1 related antibody; PP791 antibody; RP4 765A10.3 antibody; Uncharacterized protein KIAA0319 like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Dyslexia-associated protein KIAA0319-like protein (479-718AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Possible role in axon guidance through interaction with RTN4R.; (Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system.
Gene References into Functions
  1. Optic nerve damage may change retinal architecture to allow greater penetration of an AAV2 virus to transduce several additional cell types in the inner nuclear layer. PMID: 29204649
  2. AAVR directly binds to AAV2 particles, and that anti-AAVR antibodies efficiently block AAV2 infection; moreover, genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection PMID: 26814968
  3. Results identify KIAA0319L as novel susceptibility loci for Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). KIAA0319L was overexpressed in peripheral blood cells of SSc and SLE patients compared with healthy controls. PMID: 23740937
  4. KIAA0319L remains an intriguing positional and functional candidate for RD, especially when considered alongside the supporting evidence for its homolog KIAA0319 on chromosome 6p. PMID: 19085271
Subcellular Location
Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity
Expressed in cortical neurons in the brain cortex (at protein level).
Database Links

HGNC: 30071

OMIM: 613535

KEGG: hsa:79932

STRING: 9606.ENSP00000318406

UniGene: Hs.456507

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