KIAA1324 Antibody

Code CSB-PA064264
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA064264(KIAA1324 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA064264(KIAA1324 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
KIAA1324
Alternative Names
EIG121 antibody; Estrogen induced gene 121 antibody; Estrogen-induced gene 121 protein antibody; Hypothetical protein LOC57535 antibody; K1324_HUMAN antibody; KIAA1324 antibody; MABA1 antibody; MGC150624 antibody; UPF0577 protein KIAA1324 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human KIAA1324
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5.
Gene References into Functions
  1. it was found that EIG121 exerted dual functions in the regulation of autophagy and stemness not only in normal JEC cells but also JEC obtained CSCs. These findings could be useful for developing targeted therapies for endometrial carcinoma PMID: 28656197
  2. The STR in the upstream regulatory region of EIG121 is highly polymorphic, but is not associated with the risk of developing breast or endometrial cancer in the cohorts analysed here PMID: 27230222
  3. A tumor suppressive role of KIAA1324 via inhibition of GRP78 oncoprotein activities in gastric cancer PMID: 26045166
  4. EIG121 may protect cells from cell death by upregulating the autophagy pathway. PMID: 21072319
  5. High expression of ERalpha and the estrogen-induced gene EIG121 predicts shorter overall survival in patients with high-grade serous ovarian carcinoma. PMID: 21102415
  6. Down-regulation of KIAA1324 protein is associated with endometrial cancer PMID: 16322283

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Subcellular Location
Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
UPF0577 family
Tissue Specificity
Expressed in normal endometrium but overexpressed in endometroid tumors.
Database Links

HGNC: 29618

OMIM: 611298

KEGG: hsa:57535

UniGene: Hs.708190

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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