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KIF20B Antibody, FITC conjugated

Datasheet
Code CSB-PA839399LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KIF20B Polyclonal antibody
Uniprot No.
Q96Q89
Target Names
KIF20B
Alternative Names
Cancer/testis antigen 90 antibody; CT90 antibody; KI20B_HUMAN antibody; KIF20B antibody; Kinesin-like protein KIF20B antibody; Kinesin-related motor interacting with PIN1 antibody; KRMP1 antibody; M-phase phosphoprotein 1 antibody; MPHOSPH1 antibody; MPP 1 antibody; Mpp1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Kinesin-like protein KIF20B protein (1607-1731AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.
Gene References into Functions
  1. MPP1 is a new mitotic molecular motor required for completion of cytokinesis PMID: 12740395
Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cell projection, axon. Cell projection, growth cone.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Tissue Specificity
Brain, ovary, kidney and testis (at protein level). Overexpressed in bladder cancer cells (at protein level). Expressed in testis. Overexpressed in bladder cancer cells.
Database Links

HGNC: 7212

OMIM: 605498

KEGG: hsa:9585

STRING: 9606.ENSP00000260753

UniGene: Hs.240

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