KIFC3 Antibody

Code CSB-PA887134ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA887134ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA887134ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KIFC3 Polyclonal antibody
Uniprot No.
Target Names
KIFC3
Alternative Names
DKFZp686D23201 antibody; FLJ34694 antibody; Kifc3 antibody; KIFC3_HUMAN antibody; Kinesin family member C3 antibody; Kinesin-like protein KIFC3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Kinesin-like protein KIFC3 protein (140-390AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance.
Gene References into Functions
  1. Data indicate that E-cadherin ubiquitination consistently increases after depletion of kinesin-like protein KIFC3 or ubiquitin-specific protease USP47. PMID: 25253721
  2. KIFC3 may guide free microtubules to their destination at the bridge and/or may slide and crosslink central bridge microtubules in order to stage the cells for abscission. PMID: 24275865
  3. KifC3 may play a regulatory role in minus-end directed peroxisomal transport for example by blocking the motor function of dynein at peroxisomes. PMID: 23954441
  4. High expression of KIFC3 is associated with docetaxel resistance in breast cancer. PMID: 19789344
Subcellular Location
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle membrane; Peripheral membrane protein.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Database Links

HGNC: 6326

OMIM: 604535

KEGG: hsa:3801

STRING: 9606.ENSP00000368976

UniGene: Hs.23131

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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