KIR2DS5 Antibody, FITC conjugated

1. KIR2DS5 gene may be protective against hypertension. PMID: 29105364
2. The presence ofKIR2DS5 reduced the risk of endometriosis if a female possessed alleles from group C2 of HLA-C. PMID: 25724317
3. The presence of KIR2DS2/2DL2 with KIR2DS5 abrogated the risk of KIR2DS2/2DL2 and the protective benefit of KIR2DS5. PMID: 24571473
4. genetic polymorphism impacts glycosylation and protein expression level PMID: 24269691
5. The activating KIR2DS5 gene was significantly increased in thyroid ancer patients compared to the controls. PMID: 22836040
6. Data indicate that killer-cell immunoglobulin-like receptors (KIRs)activator (KIR3DS1 and KIR2DS5) and inhibitory (KIR2DL5) genes are associated with severe pandemic influenza A (H1N1) 2009 infections. PMID: 22652695
7. In summary, KIR polymorphisms may be involved in the development of Epstein-Barr virus associated hemophagocytic lymphohistiocytosis, with KIR2DS5 promoting susceptibility to this disease. PMID: 22376216
8. increase in the allele distribution in northern province of Tehran compared with that reported for the southern Iran population PMID: 21867738
9. predisposition to systemic lupus erythematosus was associated with GTGT deletion at the SLC11A1 3'UTR, presence of KIR2DS2 +/KIR2DS5 +/KIR3DS1 + profile, increased number of stimulatory KIR genes and European and Amerindian ancestries PMID: 21233146
10. The presence of KIR2DS5 gene protects human from endometriosis, ankylosing spondylitis, and acute rejection of kidney graft. PMID: 20865034
11. reduced allele frequency in African Americans PMID: 19410616
12. Donor activating KIR2DS5 may improve disease-free survival in non T-cell-depleted haploidentical hematopoietic stem cell transplantation. PMID: 18315912
13. Positive linkage disequilibrium was seen and between KIR3DS1 and KIR2DS5. PMID: 12559621
14. Carriage of activating 2ds5 was increased in patient with herpes virus RDs. PMID: 17592337
15. The most frequent allele found in 132 cell lines from International Workshop samples is KIR2DS5*005, an allele characteristic of African populations. PMID: 18498296
16. The stimulatory KIR2DS5 gene was associated with improved leukemia free survival. PMID: 18555529
17. KIR2DS5 gene codes for a surface receptor triggering natural killer cell function. PMID: 18624290
18. The level of KIR2DS5 surface expression was impacted by residue 47 but that variation at several residues in the D2 domain of KIR2DS5 ultimately had a more profound effect. PMID: 18682925
19. Lack of activation KIR2DS5 may play an important role in the development of bronchiolitis obliterans but not in the control of cytomegalovirus reactivation after lung transplantation. PMID: 18765192
20. KIR2DS1 incompatibilities increased risk of relapse after allogeneic hematopoietic stem cell transplantation PMID: 19500138

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HGNC: 6337

OMIM: 604956

KEGG: hsa:3810

UniGene: Hs.744266