KY Antibody, FITC conjugated

Datasheet

Code	CSB-PA012702LC01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KY Polyclonal antibody

Uniprot No.

Q8NBH2

Target Names

Alternative Names

KY antibody; KY_HUMAN antibody; Kyphoscoliosis peptidase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Kyphoscoliosis peptidase protein (23-170AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.

Gene References into Functions

This study shown Kyphoscoliosis peptidase (KY) mutation causes a novel congenital myopathy with core targetoid defects in two bother. PMID: 27484770
Homozygous KY mutation was identified as a cause of progressive hereditary spastic paraplegia. High KY transcript levels were demonstrated in muscular organs and lower expression in the CNS. PMID: 28488683
Homozygous c.1071delG, p.(Thr358Leufs*3) variant of KY causes neuromuscular disorder by introducing a premature stop codon. PMID: 27485408
KY expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614

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Involvement in disease

Myopathy, myofibrillar, 7 (MFM7)

Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.

Protein Families

Transglutaminase-like superfamily

Tissue Specificity

Highly expressed in skeletal muscle.

Database Links

HGNC: 26576

OMIM: 605739

KEGG: hsa:339855

STRING: 9606.ENSP00000397598

UniGene: Hs.146730

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