KYAT3 Antibody

Datasheet

Code	CSB-PA740996LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA740996LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA740996LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KYAT3 Polyclonal antibody

Uniprot No.

Q6YP21

Target Names

KYAT3

Alternative Names

CCBL 2 antibody; Cysteine conjugate beta lyase 2 antibody; Cysteine S conjugate beta lyase 2 antibody; Cysteine-S-conjugate beta-lyase 2 antibody; DKFZp547N1117 antibody; DKFZp667D0223 antibody; KAT 3 antibody; KAT III antibody; KAT3 antibody; KAT3_HUMAN antibody; KATIII antibody; kyat3 antibody; Kynurenine aminotransferase 3 antibody; Kynurenine aminotransferase III antibody; Kynurenine oxoglutarate transaminase 3 antibody; Kynurenine oxoglutarate transaminase III antibody; Kynurenine--glyoxylate transaminase antibody; Kynurenine--oxoglutarate transaminase 3 antibody; Kynurenine--oxoglutarate transaminase III antibody; MGC9398 antibody; RBM1 antibody; RBMX L1 antibody; RBMXL 1 antibody; RBMXL1 antibody; RNA binding motif protein X linked like 1 antibody; RP11 82K18.3 antibody; RP4 531M19.2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Kynurenine--oxoglutarate transaminase 3 protein (1-454AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KYAT3 Antibody (Product code: CSB-PA740996LA01HU) is Non-conjugated. For KYAT3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA740996LB01HU	KYAT3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA740996LC01HU	KYAT3 Antibody, FITC conjugated
Biotin	CSB-PA740996LD01HU	KYAT3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).

Gene References into Functions

Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
human KAT III/CCBL2 possesses cysteine S-conjugate beta-lyase activity, as does mouse KAT II PMID: 25231977
The haplotype of KAT III gene CGCTCT may have effect on the function of this enzyme in formation of kynurenic acid in some patients with major depressive episodes. PMID: 21492941
Using shotgun mass spectrometry, it was found that this protein is differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19165527

Protein Families

Class-I pyridoxal-phosphate-dependent aminotransferase family

Database Links

HGNC: 33238

OMIM: 610656

KEGG: hsa:56267

STRING: 9606.ENSP00000260508

UniGene: Hs.481898

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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