LACTB2 Antibody, FITC conjugated

Code CSB-PA706635LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LACTB2 Polyclonal antibody
Uniprot No.
Target Names
LACTB2
Alternative Names
Beta lactamase like protein 2 antibody; Beta-lactamase-like protein 2 antibody; CGI 83 antibody; CGI-83 antibody; LACB2_HUMAN antibody; Lactamase beta 2 antibody; LACTB2 antibody; MGC112672 antibody; MGC140671 antibody; MGC7674 antibody; OTTHUMP00000226691 antibody; OTTHUMP00000226692 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Endoribonuclease LACTB2 protein (6-288AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Gene References into Functions
  1. This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism PMID: 27005419
  2. this study discovered that LACTB2 is an endoribonuclease that is involved in the turnover of mitochondrial RNA, and is essential for mitochondrial function in human cells. PMID: 26826708
  3. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer PMID: 25823027
Subcellular Location
Mitochondrion matrix.
Protein Families
Metallo-beta-lactamase superfamily, Glyoxalase II family
Database Links

HGNC: 18512

KEGG: hsa:51110

STRING: 9606.ENSP00000276590

UniGene: Hs.118554

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