LHX3 Antibody, Biotin conjugated

Datasheet
Code CSB-PA871386LD01HU
Size US$299
Uniprot No. Q9UBR4
Protocols ELISA Protocol
Immunogen Recombinant Human LIM/homeobox protein Lhx3 protein (233-389AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias LIM/homeobox protein Lhx3 (LIM homeobox protein 3), LHX3
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names LHX3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1.
Involvement in disease Pituitary hormone deficiency, combined, 3 (CPHD3)
Subcellular Location Nucleus
Database Links

HGNC: 6595

OMIM: 221750

KEGG: hsa:8022

STRING: 9606.ENSP00000360811

UniGene: Hs.148427

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