LHX6 Antibody

Datasheet

Code	CSB-PA891795ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA891795ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LHX6 Polyclonal antibody

Uniprot No.

Q9UPM6

Target Names

LHX6

Alternative Names

LHX 6 antibody; LHX 6.1 antibody; LHX6 antibody; LHX6.1 antibody; LHX6_HUMAN antibody; LIM homeobox 6 antibody; LIM homeobox protein 6 antibody; LIM homeodomain protein 6.1 antibody; LIM/homeobox protein Lhx6 antibody; LIM/homeobox protein Lhx6.1 antibody; MGC119542 antibody; MGC119544 antibody; MGC119545 antibody; OTTHUMP00000064113 antibody; OTTHUMP00000064114 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human LIM/homeobox protein Lhx6 protein (114-363AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.

Gene References into Functions

that down-regulation of miR-214 may reverse acquired resistance to erlotinib in NSCLC through mediating its direct target gene LHX6 expression. PMID: 28396596
LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt/beta-catenin signaling pathway. PMID: 26129710
LHX6 is a putative tumour suppressor gene with epigenetic silencing in lung cancer. PMID: 24157876
LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis PMID: 23229549
found positive association of LHX6 with Tourette syndrome in some European populations, not others. LHX6 demonstrates a high degree of population differentiation and is correlated with the North to South axis of European genetic variation. PMID: 22435649
hLHX6.1 could be a new tumor suppressor gene in the cervix. PMID: 21240459
Hypermethylation of LHX6 is associated with cervical cancer. PMID: 20428825
differentially methylated hypermethylation of LHX6 is a good cancer marker in HNSCC as well as in other kinds of neoplasias and confirm the importance of searching for markers of epigenetic dysregulation in cancer PMID: 16732332

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Subcellular Location

Nucleus.

Database Links

HGNC: 21735

OMIM: 608215

KEGG: hsa:26468

STRING: 9606.ENSP00000377854

UniGene: Hs.103137

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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