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LHX6 Antibody

Datasheet
Code CSB-PA891795ESR2HU
Size US$166
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Image
  • Immunohistochemistry(IHC) 1- LHX6 Antibody

    Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA891795ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LHX6 Polyclonal antibody
Uniprot No.
Q9UPM6
Target Names
LHX6
Alternative Names
LHX 6 antibody; LHX 6.1 antibody; LHX6 antibody; LHX6.1 antibody; LHX6_HUMAN antibody; LIM homeobox 6 antibody; LIM homeobox protein 6 antibody; LIM homeodomain protein 6.1 antibody; LIM/homeobox protein Lhx6 antibody; LIM/homeobox protein Lhx6.1 antibody; MGC119542 antibody; MGC119544 antibody; MGC119545 antibody; OTTHUMP00000064113 antibody; OTTHUMP00000064114 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human LIM/homeobox protein Lhx6 protein (114-363AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

LHX6 Antibodies

LHX6 Proteins

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Target Background

Function
Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
Gene References into Functions
  1. that down-regulation of miR-214 may reverse acquired resistance to erlotinib in NSCLC through mediating its direct target gene LHX6 expression. PMID: 28396596
  2. LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt/beta-catenin signaling pathway. PMID: 26129710
  3. LHX6 is a putative tumour suppressor gene with epigenetic silencing in lung cancer. PMID: 24157876
  4. LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis PMID: 23229549
  5. found positive association of LHX6 with Tourette syndrome in some European populations, not others. LHX6 demonstrates a high degree of population differentiation and is correlated with the North to South axis of European genetic variation. PMID: 22435649
  6. hLHX6.1 could be a new tumor suppressor gene in the cervix. PMID: 21240459
  7. Hypermethylation of LHX6 is associated with cervical cancer. PMID: 20428825
  8. differentially methylated hypermethylation of LHX6 is a good cancer marker in HNSCC as well as in other kinds of neoplasias and confirm the importance of searching for markers of epigenetic dysregulation in cancer PMID: 16732332

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Subcellular Location
Nucleus.
Database Links

HGNC: 21735

OMIM: 608215

KEGG: hsa:26468

STRING: 9606.ENSP00000377854

UniGene: Hs.103137

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