LMOD1 Antibody

Datasheet

Code	CSB-PA013013ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA013013ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013013ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LMOD1 Polyclonal antibody

Uniprot No.

P29536

Target Names

LMOD1

Alternative Names

1D antibody; 64 kDa autoantigen 1D antibody; 64 kDa autoantigen 1D3 antibody; 64 kDa autoantigen D1 antibody; 9530015K06Rik antibody; D1 antibody; Leiomodin antibody; Leiomodin-1 antibody; Lmod1 antibody; LMOD1_HUMAN antibody; muscle form antibody; SM LMOD antibody; SM-Lmod antibody; SMLMOD antibody; Smooth muscle leiomodin antibody; Thyroid associated ophthalmopathy autoantigen antibody; Thyroid-associated ophthalmopathy autoantigen antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Leiomodin-1 protein (29-187AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Mediates nucleation of actin filaments.

Gene References into Functions

Loss of LMOD1 results in a reduction of filamentous actin, elongated cytoskeletal dense bodies, and impaired intestinal smooth muscle contractility. PMID: 28292896
Key role for miR-214 in modulation of MEF2C-MYOCD-LMOD1 signaling. PMID: 27144530
Lmod1 is a new SMC-restricted SRF/MYOCD target gene. PMID: 22157009
Lmod1 is a component of the smooth muscle contractile apparatus extractable by high salt, not a transmembrane protein as previously predicted. PMID: 11350761
Lmod1, formerly the 64kD human autoantigen D1, is expressed in smooth muscle and striated extraocular slow muscle fibers, colocalized with myosin in the contractile apparatus. Protein levels are unaltered by hyperthyroidism. PMID: 10520227
Lmod1 is a member of the Tropomodulin family of actin binding proteins, and is most highly expressed in smooth muscle. PMID: 11318603

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Subcellular Location

Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton.

Protein Families

Tropomodulin family

Tissue Specificity

Detected in lung vascular smooth muscle (at protein level). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle. Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine.

Database Links

HGNC: 6647

OMIM: 602715

KEGG: hsa:25802

STRING: 9606.ENSP00000356257

UniGene: Hs.519075

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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