LRP10 Antibody

Code CSB-PA220915
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human brain tissue using LRP10 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRP10 Polyclonal antibody
Uniprot No.
Target Names
LRP10
Alternative Names
LRP10 antibody; MSTP087 antibody; SP220 antibody; UNQ389/PRO724Low-density lipoprotein receptor-related protein 10 antibody; LRP-10 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human LRP10.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.
Gene References into Functions
  1. In Mayer-Rokitansky-Kuster-Hauser syndrome in monoztgotic twins, LRP10 was identified as one of the candidate genes. PMID: 25492683
  2. Increased expression of LRP10 in human neuroblastoma SH-SY5Y cells induces the accumulation of mature APP in the Golgi and reduces its presence at the cell surface and its processing into Abeta. PMID: 22734645
  3. LRP10 may interfere with the formation of the beta-catenin/TCF complex and/or its binding to target DNA in the nucleus, and that the extracellular domain of LRP10 is critical for inhibition of the canonical Wnt/beta-catenin signaling pathway. PMID: 20093106
Subcellular Location
Membrane; Single-pass type I membrane protein. Membrane, coated pit.
Protein Families
LDLR family
Tissue Specificity
Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart.
Database Links

HGNC: 14553

OMIM: 609921

KEGG: hsa:26020

STRING: 9606.ENSP00000352601

UniGene: Hs.525232

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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