LRRC4C Antibody

Datasheet

Code	CSB-PA888027LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA888027LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human glioma using CSB-PA888027LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA888027LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LRRC4C Polyclonal antibody

Uniprot No.

Q9HCJ2

Target Names

LRRC4C

Alternative Names

LRRC4C; KIAA1580; NGL1; UNQ292/PRO331; Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; NGL-1

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Leucine-rich repeat-containing protein 4C protein (201-500AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LRRC4C Antibody (Product code: CSB-PA888027LA01HU) is Non-conjugated. For LRRC4C Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA888027LB01HU	LRRC4C Antibody, HRP conjugated	ELISA
FITC	CSB-PA888027LC01HU	LRRC4C Antibody, FITC conjugated
Biotin	CSB-PA888027LD01HU	LRRC4C Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

May promote neurite outgrowth of developing thalamic neurons.

Gene References into Functions

These data suggest that the proband's autism may be due to the inheritance of disruptions in both DPP6 and LRRC4C, and may highlight the importance of the netrin G family and potassium channel interacting molecules in neurodevelopmental disorders. PMID: 27759917
Interaction between the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses. PMID: 23986473
netrin-G1 functions as an important component of the NGL-1 receptor to promote TCA outgrowth and that membrane-bound netrins can participate in receiving axonal signaling pathways. PMID: 14595443
NGL-1 is most abundant in the striatum and the cerebral cortex--the intermediate and final targets, of thalamocortical axons; surface-bound NGL-1 stimulates, but soluble NGL-1 disrupts, the growth of embryonic thalamic axons. PMID: 14595443

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show v

Database Links

HGNC: 29317

OMIM: 608817

KEGG: hsa:57689

STRING: 9606.ENSP00000278198

UniGene: Hs.745123

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Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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