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LTN1 Antibody, FITC conjugated

Datasheet
Code CSB-PA026646LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LTN1 Polyclonal antibody
Uniprot No.
O94822
Target Names
LTN1
Alternative Names
LTN1 antibody; C21orf10 antibody; C21orf98 antibody; KIAA0714 antibody; RNF160 antibody; ZNF294 antibody; HSPC087E3 ubiquitin-protein ligase listerin antibody; EC 2.3.2.27 antibody; RING finger protein 160 antibody; RING-type E3 ubiquitin transferase listerin antibody; Zinc finger protein 294 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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LTN1 Proteins

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Target Background

Function
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
Gene References into Functions
  1. E3 ligase listerin accesses nascent polypeptides stalled at the Sec61 translocon via a gap in the ribosome-translocon junction near the Sec61 lateral gate. PMID: 25877867
  2. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
Subcellular Location
Cytoplasm, cytosol.
Protein Families
LTN1 family
Database Links

HGNC: 13082

OMIM: 613083

KEGG: hsa:26046

STRING: 9606.ENSP00000373846

UniGene: Hs.288773

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