MAGEA9 Antibody

1. MAGE-A9 overexpression promoted cell proliferation, colony formation, migration, chemoresistance, and tumorigenicity in the context of EpCAM+ HCC cells, whereas MAGE-A9 knockdown significantly inhibited anchorage-dependent and spheroid colony formation and in vivo tumorigenicity. PMID: 29138811
2. potential X-linked candidate for the CNV67-related spermatogenic failure phenotype PMID: 28339631
3. High expression levels of MAGE-A9 are correlated with lung adenocarcinoma. PMID: 26717042
4. The results showed that the high expression of MAGE-A9 protein in NSCLC tumor cells were commonly present in squamous cell carcinomas. It was also related to larger tumor diameter, lymph node metastasis and later stage grouping with TNM classification PMID: 25755744
5. These data are the first to indicate that MAGE-A9 expression is a valuable prognostic biomarker for HCC and that high MAGE-A9 expression suggests unfavorable survival outcomes in HCC patients PMID: 25315972
6. High expression of MAGE-A9 indicates unfavorable survival outcome in laryngeal squamous cell carcinoma patients. PMID: 25400753
7. The data suggest that MAGE-A9 expression is correlated with malignant attributes of invasive ductal breast cancer PMID: 25445503
8. MAGE-A9 and MAGE-A11 are tumor-specific antigens and not only DNA hypermethylation but also histone deacetylation is responsible for the mechanism underlying MAGE-A9 and MAGE-A11 gene silencing. PMID: 24316396
9. May provide suitable targets for immunotherapy of renal cell carcinoma. PMID: 15900605
10. Overexpression of MAGE-A9 is associated with bladder cancer. PMID: 19533752

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HGNC: 6807

OMIM: 300342

KEGG: hsa:4108

STRING: 9606.ENSP00000298974

UniGene: Hs.460974