MAN2C1 Antibody

Datasheet

Code	CSB-PA878885LA01HU
Size	US$166
	Order now
Image	Immunohistochemistry analysis of human appendix tissue using CSB-PA878885LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA878885LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MAN2C1 Polyclonal antibody

Uniprot No.

Q9NTJ4

Target Names

MAN2C1

Alternative Names

MAN2C1 antibody; MANA antibody; MANA1Alpha-mannosidase 2C1 antibody; EC 3.2.1.24 antibody; Alpha mannosidase 6A8B antibody; Alpha-D-mannoside mannohydrolase antibody; Mannosidase alpha class 2C member 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Alpha-mannosidase 2C1 protein (746-969AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MAN2C1 Antibody (Product code: CSB-PA878885LA01HU) is Non-conjugated. For MAN2C1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA878885LB01HU	MAN2C1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878885LC01HU	MAN2C1 Antibody, FITC conjugated
Biotin	CSB-PA878885LD01HU	MAN2C1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm.

Gene References into Functions

MAN2C1 may contribute to the verbal difficulties observed in microduplications and to the intellectual disability of microdeletion syndromes PMID: 27355585
Man2C1 has dual functions: one in glycan catabolism and another in apoptotic signaling. PMID: 23486476
MAN2C1 binds PTEN thereby inhibiting its phosphatidylinositol 3,4,5 triphosphate phosphatase activity PMID: 21556061
MAN2C1 methylation levels modify cumulative traumatic burden on risk of post traumatic stress disorder PMID: 21508515
regulation of Man2C1 expression is essential for maintaining efficient protein N-glycosylation PMID: 20978011
Reduced antibody response to BSA was observed in transgenic mice, suggesting that specific antibody response to tumor antigens might be suppressed by hMan2c1 transgene. PMID: 19572206
plays an important role in preventing oncosis-like death in BJAB cells PMID: 12643454
Results suggest that inhibition of alpha-mannosidase Man2c1 gene expression enhances adhesion of Jurkat T cells. PMID: 16721356
Inhibition of MAN2C1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis. PMID: 19018777

Hide All

Subcellular Location

Cytoplasm.

Protein Families

Glycosyl hydrolase 38 family

Database Links

HGNC: 6827

OMIM: 154580

KEGG: hsa:4123

STRING: 9606.ENSP00000267978

UniGene: Hs.26232

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
If CAPTCHA verification fails, click to refresh the CAPTCHA and try again.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address