MARS2 Antibody, HRP conjugated

Code CSB-PA836221LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MARS2 Polyclonal antibody
Uniprot No.
Target Names
MARS2
Alternative Names
mars2 antibody; Methionine tRNA ligase 2 antibody; Methionine tRNA ligase 2 mitochondrial antibody; Methionine tRNA ligase antibody; Methionine tRNA synthetase 2 antibody; Methionine--tRNA ligase antibody; Methionyl tRNA synthetase 2 mitochondrial antibody; Methionyl tRNA synthetase mitochondrial antibody; Methionyl-tRNA synthetase 2 antibody; MetRS antibody; mitochondrial antibody; Mitochondrial methionine tRNA ligase antibody; Mitochondrial methionyl tRNA synthetase antibody; Mitochondrial methionyl-tRNA synthetase antibody; MtMetRS antibody; SYMM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Methionine--tRNA ligase, mitochondrial protein (225-460AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. Novel, compound heterozygous, single-nucleotide variants in MARS2 associated with developmental delay, poor growth, and sensorineural hearing loss PMID: 25754315
  2. MARS2 is mutated in Autosomal Recessive Spastic Ataxia with Leukoencephalopathy patients. PMID: 22448145
  3. Sequence analysis of mitochondrial MetRS indicates that this protein contains consensus motifs characteristic of class I aminoacyl-tRNA synthetase but lacks Zn2+ binding motif and C-terminal dimerization region found in MetRSs from various organisms. PMID: 15274629
Involvement in disease
Spastic ataxia 3, autosomal recessive (SPAX3); Combined oxidative phosphorylation deficiency 25 (COXPD25)
Subcellular Location
Mitochondrion matrix.
Protein Families
Class-I aminoacyl-tRNA synthetase family
Database Links

HGNC: 25133

OMIM: 609728

KEGG: hsa:92935

STRING: 9606.ENSP00000282276

UniGene: Hs.744330

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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