MAST1 Antibody

Code CSB-PA897529LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA897529LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA897529LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA897529LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody
Uniprot No.
Target Names
MAST1
Alternative Names
9430008B02Rik antibody; KIAA0973 antibody; MAST 1 antibody; MAST1 antibody; MAST1_HUMAN antibody; Microtubule associated serine/threonine kinase 1 antibody; Microtubule associated serine/threonine protein kinase 1 antibody; Microtubule-associated serine/threonine-protein kinase 1 antibody; SAST 124 antibody; SAST 170 antibody; SAST antibody; SAST170 antibody; Syntrophin associated serine/threonine kinase antibody; Syntrophin associated serine/threonine protein kinase antibody; Syntrophin-associated serine/threonine-protein kinase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MAST1 Antibody (Product code: CSB-PA897529LA01HU) is Non-conjugated. For MAST1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA897529LB01HU MAST1 Antibody, HRP conjugated ELISA
FITC CSB-PA897529LC01HU MAST1 Antibody, FITC conjugated
Biotin CSB-PA897529LD01HU MAST1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description
MAST1 polyclonal antibody CSB-PA897529LA01HU was produced in the rabbit immunized by using the Recombinant Human Microtubule-associated serine/threonine-protein kinase 1 protein (687-879AA) as the immunogen. The target protein MAST1 is essential for correct brain development, and appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Diseases associated with MAST1 include Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations and Cerebellar Hypoplasia.
This Rabbit anti-Homo sapiens (Human) MAST1 Polyclonal antibody was tested in the ELISA, IHC and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the MAST1 proteins of human-origin and may be used to detect the endogenous levels of MAST1 protein.

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Applications : Immunohistochemistry (IHC)

Sample type: tissues

Review: Immunohistochemical staining of USP1 and MAST1 in human clinical samples. Representative immunohistochemical staining images of endogenous USP1 and MAST1 in (A) lung, (B) colon, and (C) breast cancer tissues vs. normal tissues. All IHC images were quantified with an H-score. A two-tailed t-test was used, and P values are indicated. Scale bar = 30 µm.

By Anonymous

Target Background

Function
Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
Gene References into Functions
  1. Overexpression of MAST1 or MAST2 gene fusions has a proliferative effect both in vitro and in vivo in breast cancer cell lines. PMID: 22101766
  2. Discusses cloning of Sast, the mouse ortholog of human MAST1. PMID: 10404183
  3. Discusses cloning of Sast124, the rat ortholog of MAST1. PMID: 12614677
Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite.
Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family
Tissue Specificity
Expressed in fetal brain.
Database Links

HGNC: 19034

OMIM: 612256

KEGG: hsa:22983

STRING: 9606.ENSP00000251472

UniGene: Hs.227489

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