MCIDAS Antibody

Datasheet

Code	CSB-PA518689LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA518689LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MCIDAS Polyclonal antibody

Uniprot No.

D6RGH6

Target Names

MCIDAS

Alternative Names

IDAS antibody; Mci antibody; MCI_HUMAN antibody; Multicilin antibody; Protein Idas antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Multicilin protein (3-110AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MCIDAS Antibody (Product code: CSB-PA518689LA01HU) is Non-conjugated. For MCIDAS Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA518689LB01HU	MCIDAS Antibody, HRP conjugated	ELISA
FITC	CSB-PA518689LC01HU	MCIDAS Antibody, FITC conjugated
Biotin	CSB-PA518689LD01HU	MCIDAS Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.

Gene References into Functions

MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia.MCIDAS regulates CCNO and FOXJ1 expression. PMID: 25048963
The properties of the Idas-Geminin complex suggest it as the functional form of Idas and provide a possible mechanism to modulate Geminin activity PMID: 24064211
Idas as a novel Geminin binding partner, implicated in cell cycle progression, and a putative regulator of proliferation-differentiation decisions during development. PMID: 21543332

Subcellular Location

Nucleus.

Protein Families

Geminin family

Database Links

HGNC: 40050

OMIM: 614086

KEGG: hsa:345643

STRING: 9606.ENSP00000426359

UniGene: Hs.394578

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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