MED21 Antibody

Datasheet

Citations (1)

Code	CSB-PA070304
Size	US$119
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q13503

Target Names

MED21

Alternative Names

MED21 antibody; SRB7 antibody; SURB7 antibody; Mediator of RNA polymerase II transcription subunit 21 antibody; Mediator complex subunit 21 antibody; RNA polymerase II holoenzyme component SRB7 antibody; RNAPII complex component SRB7 antibody; hSrb7 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human Srb7.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:20000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with 'Actionable'Pulmonary Nodules C Auger,Cancers,2023

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Western blot

Sample type: cells

Review: MED21 had the highest sensitivity,with 79% sensitivity in the training cohort and 83% sensitivity in the testing.

By Anonymous

Target Background

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene References into Functions

Co-expressed yeast MED21 and MED7 in E. coli to determine structure. PMID: 15710619
Blocking MED1/MED21 expression caused hyperproliferation of keratinocytes PMID: 20520624

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 21 family

Database Links

HGNC: 11473

OMIM: 603800

KEGG: hsa:9412

STRING: 9606.ENSP00000282892

UniGene: Hs.286145

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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