MED30 Antibody, FITC conjugated

Datasheet

Code	CSB-PA822225LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MED30 Polyclonal antibody

Uniprot No.

Q96HR3

Target Names

MED30

Alternative Names

MED30 antibody; MED30_HUMAN antibody; Mediator complex subunit 30 antibody; Mediator of RNA polymerase II transcription subunit 30 antibody; THRAP6 antibody; Thyroid hormone receptor-associated protein 6 antibody; Thyroid hormone receptor-associated protein complex 25 kDa component antibody; TRAP/Mediator complex component TRAP25 antibody; Trap25 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mediator of RNA polymerase II transcription subunit 30 protein (67-165AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene References into Functions

MED30 seems to be involved in the progression of the renal cell carcinoma (RCC). PMID: 29661722
Knockdown of MED30 led to reduction of the tumour parameters proliferation, migration, and invasion in the bladder cancer (BCa) cell lines. PMID: 29187445
analysis of a novel transcript of MED30, termed MED30 short (MED30s) generated by alternative splicing PMID: 20493979
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. PMID: 11909976

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 30 family

Tissue Specificity

Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

Database Links

HGNC: 23032

OMIM: 610237

KEGG: hsa:90390

STRING: 9606.ENSP00000297347

UniGene: Hs.492612

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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