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MPDU1 Antibody, FITC conjugated

Datasheet
Code CSB-PA014744LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MPDU1 Polyclonal antibody
Uniprot No.
O75352
Target Names
MPDU1
Alternative Names
MPDU1; Mannose-P-dolichol utilization defect 1 protein; Suppressor of Lec15 and Lec35 glycosylation mutation homolog; SL15
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mannose-P-dolichol utilization defect 1 protein (1-36AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
Gene References into Functions
  1. These experiments also confirmed that protein levels of CEACAM-1, which functions in cell adhesion, is dependent on LLO biosynthesis in vivo. Kato III cells and the MPDU1-rescued Kato IIIM cells therefore provide a novel model to examine the consequences of defective LLO biosynthesis both in vitro and in vivo. PMID: 29671116
  2. Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors. PMID: 22363504
Involvement in disease
Congenital disorder of glycosylation 1F (CDG1F)
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
MPDU1 (TC 2.A.43.3) family
Database Links

HGNC: 7207

OMIM: 604041

KEGG: hsa:9526

STRING: 9606.ENSP00000250124

UniGene: Hs.246381

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