MSC Antibody, FITC conjugated

Code CSB-PA015025LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MSC Polyclonal antibody
Uniprot No.
Target Names
MSC
Alternative Names
ABF-1 antibody; ABF1 antibody; Activated B cell factor 1 antibody; Activated B-cell factor 1 antibody; bHLHa22 antibody; Class A basic helix-loop-helix protein 22 antibody; Msc antibody; MUSC_HUMAN antibody; Musculin antibody; MYOR antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Musculin protein (3-143AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
Gene References into Functions
  1. this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity PMID: 28612433
  2. results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation. PMID: 25070843
  3. role in repressing lymphotoxin alpha PMID: 15052269
  4. ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. PMID: 18368067
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in lymphoid tissues, B-cell lines and activated B-cells.
Database Links

HGNC: 7321

OMIM: 603628

KEGG: hsa:9242

STRING: 9606.ENSP00000321445

UniGene: Hs.442619

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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