MUC3A Antibody

Datasheet

Code	CSB-PA130507
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA130507(MUC3A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA130507(MUC3A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q02505

Target Names

MUC3A

Alternative Names

MUC3A antibody; MUC3 antibody; Mucin-3A antibody; MUC-3A antibody; Intestinal mucin-3A antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human MUC3A

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.

Gene References into Functions

MUC3A may have a role in poor prognosis in localized clear-cell renal cell carcinoma PMID: 27374181
DNA hypomethylation in the 5'-flanking region of the MUC3A gene plays an important role in MUC3A expression in carcinomas of various organs. PMID: 20510874
has highly conserved amino and carboxyl termini, suggesting a recent duplication of the entire ancestral gene PMID: 12958310
MUC3 is overexpressed in renal clear cell carcinoma, and the MUC3 expression ratio is greater in nuclear grade 3 than in grades 1 and 2 (low grades) tumor. These findings suggest the implication of MUC3 in renal carcinogenesis. PMID: 14550470
up-regulated MUC expression by synovial tissue cells and suggest a novel role of MUC3 and MUC5AC in the pathogenesis of arthritis PMID: 18163520
We report the colonic adhesion mechanism of Lactobaillus plantarums LA318 is in part due to GAPDH binding to human ABO-type blood group antigens expressed on human colonic mucin (HCM). [HCM] PMID: 18790050
Data show that the diagnostic sensitivity for mucin was 60%, and the specificity for mucin was 100%. PMID: 19365834
Data show that special stains for mucin did not distinguish pseudocysts from neoplastic mucinous cysts. PMID: 19365837

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Subcellular Location

[Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.

Tissue Specificity

Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.

Database Links

HGNC: 7513

OMIM: 158371

KEGG: hsa:4584

STRING: 9606.ENSP00000324834

UniGene: Hs.703577

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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