MYBPH Antibody, Biotin conjugated

Datasheet

Code	CSB-PA618765LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MYBPH Polyclonal antibody

Uniprot No.

Q13203

Target Names

MYBPH

Alternative Names

bHLHe38 antibody; H protein antibody; H-protein antibody; l-myc protein antibody; l-myc-1 proto-oncogene antibody; LMYC antibody; MyBP H antibody; MyBP-H antibody; Mybph antibody; MYBPH_HUMAN antibody; myc-related gene from lung cancer antibody; MYCL antibody; Myosin binding protein H antibody; Myosin binding protein, 86-KD antibody; Myosin-binding protein H antibody; Oncogene lmyc antibody; V-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Myosin-binding protein H protein (3-159AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.

Gene References into Functions

variation in MYBPH can modulate the severity of hypertrophy in hypertrophic cardiomyopathy patients. PMID: 26969327
MyBP-H expression signals the onset of dysregulation in actin-myosin interaction; this in turn might contribute to the pathogenesis of amyotrophic lateral sclerosis. PMID: 24184715
These results suggest that MYBPH inhibits RLC and NMHC IIA, independent components of NM IIA, and negatively regulates actomyosin organization at 2 distinct steps, resulting in firm inhibition of NM IIA assembly. PMID: 23068101
MYBPH inhibited assembly competence-conferring phosphorylation of the myosin regulatory light chain (RLC) as well as activating phosphorylation of LIM domain kinase, unexpectedly through its direct physical interaction with Rho kinase 1 PMID: 22085929

Protein Families

Immunoglobulin superfamily, MyBP family

Tissue Specificity

Mainly expressed in the skeletal muscle. Slightly expressed in the left atrium and arteria mammaria interna.

Database Links

HGNC: 7552

OMIM: 160795

KEGG: hsa:4608

STRING: 9606.ENSP00000255416

UniGene: Hs.927

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Myosin Regulatory Light Chains (MYL12A and MYL12B): the New Functional Ligands for CD69, Potential Targets for Cardiac Disease or Tumors Research? Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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