NANOS1 Antibody

Code CSB-PA837878LA01HU
Size US$166
Order now
Image
  • Immunofluorescent analysis of Hela cells using CSB-PA837878LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NANOS1 Polyclonal antibody
Uniprot No.
Target Names
NANOS1
Alternative Names
EC Rep1a antibody; EC_Rep1a antibody; NANO1_HUMAN antibody; NANOS 1 antibody; Nanos homolog 1 (Drosophila) antibody; Nanos homolog 1 antibody; Nanos Homologue 1 (NANOS1) antibody; NANOS1 antibody; Nos 1 antibody; NOS-1 antibody; Nos1 antibody; OTTHUMP00000046853 antibody; Rep 1a antibody; Rep1a antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nanos homolog 1 protein (1-292AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NANOS1 Antibody (Product code: CSB-PA837878LA01HU) is Non-conjugated. For NANOS1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA837878LB01HU NANOS1 Antibody, HRP conjugated ELISA
FITC CSB-PA837878LC01HU NANOS1 Antibody, FITC conjugated
Biotin CSB-PA837878LD01HU NANOS1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion.
Gene References into Functions
  1. High NANOS expression is associated with retinoblastoma. PMID: 25100735
  2. A group of 195 patients manifesting non-obstructive azoospermia or oligozoospermia were tested for mutations of the NANOS1 gene. PMID: 23315541
  3. Single nucleotide polymorphisms in CYP26B1, NANOS1 and STRA8 genes support involvement of meiotic program initiation in modifying azoospermia and oligozoospermia risk in a Han-Chinese population PMID: 23320086
  4. NANOS1-PUMILIO2 complex, together with GEMIN3 and small noncoding RNAs, possibly regulate mRNA translation within the chromatoid body of the human germ cells. PMID: 21800163
  5. Findings describe a new function for hNanos1 as a downstream effector of E-cadherin loss contributing to tumor progression. PMID: 17047063
  6. The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression. PMID: 18223680
  7. Data demonstrated that SNAPIN interacts additionally with NANOS1 protein. This is the first report demonstrating that the N-terminal region of NANOS1 is necessary for protein binding. PMID: 19168546

Show More

Hide All

Involvement in disease
Spermatogenic failure 12 (SPGF12)
Subcellular Location
Cytoplasm, perinuclear region. Cytoplasm.
Protein Families
Nanos family
Tissue Specificity
Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermat
Database Links

HGNC: 23044

OMIM: 608226

KEGG: hsa:340719

STRING: 9606.ENSP00000393275

UniGene: Hs.591918

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*