NCAM2 Antibody, FITC conjugated

Code CSB-PA015512LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NCAM2 Polyclonal antibody
Uniprot No.
Target Names
NCAM2
Alternative Names
Cell adhesion molecule, neural, 2 antibody; MGC51008 antibody; N CAM 2 antibody; N CAM 21 antibody; N CAM2 antibody; N CAM21 antibody; N-CAM-2 antibody; NCAM 2 antibody; NCAM 21 antibody; NCAM-2 antibody; Ncam2 antibody; NCAM2_HUMAN antibody; NCAM21 antibody; Neural cell adhesion molecule 2 antibody; OCAM GPI antibody; R4B12 antibody; RB 8 neural cell adhesion molecule antibody; RB8 neural cell adhesion molecule antibody; RNCAM antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neural cell adhesion molecule 2 protein (209-333AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Gene References into Functions
  1. Our reported case raises the questions whether the NCAM2-deletion is the true cause of the autism spectrum disorder or only a risk factor and whether there might be any connection in NCAM2 with skull-size PMID: 27596683
  2. Abeta-dependent disruption of NCAM2 functions in Alzheimer's disease hippocampus contributes to synapse loss. PMID: 26611261
  3. A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain. PMID: 21300289
  4. High NCAM2 is associated with increased 5-Fluorouracil sensitivity in prostate and breast cancer. PMID: 21214674
  5. In the crystal structure, two Ig domains interact by domain swapping, as the two N-terminal beta-strands are interchanged. PMID: 18706912

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed most strongly in adult and fetal brain.
Database Links

HGNC: 7657

OMIM: 602040

KEGG: hsa:4685

STRING: 9606.ENSP00000383392

UniGene: Hs.473450

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