NDUFS6 Antibody

Code CSB-PA089578
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA089578(NDUFS6 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
NDUFS6
Alternative Names
BC059730 antibody; CI 13kA antibody; CI 13kD A antibody; CI-13kD-A antibody; CI13KDA antibody; Complex I 13kD A antibody; Complex I 13kDa subunit A antibody; Complex I mitochondrial respiratory chain 13 kD subunit antibody; Complex I-13kD-A antibody; IP13 antibody; MGC107676 antibody; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH coenzyme Q reductase) antibody; NADH dehydrogenase [ubiquinone] iron sulfur protein 6, mitochondrial antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial antibody; NADH ubiquinone oxidoreductase 13 kDa A subunit antibody; NADH-ubiquinone oxidoreductase 13 kDa-A subunit antibody; NADH:ubiquinone oxidoreductase NDUFS6 subunit antibody; NADH:ubiquinone oxidoreductase subunit S6 antibody; Ndufs6 antibody; NDUS6_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human NDUFS6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Gene References into Functions
  1. CD147 appears to regulate complex I activity and apoptosis in malignant melanoma cells by interacting with mitochondrial NDUFS6. PMID: 25470292
  2. NDUFS6, a complex I subunit gene not previously associated with complex I deficiency, was grossly underexpressed in t patient cell lines. PMID: 15372108
  3. NDUFS6 is required for the assembly and stabilization of a portion of complex I that contains a number of subunits. PMID: 17438127
Involvement in disease
Mitochondrial complex I deficiency (MT-C1D)
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
Complex I NDUFS6 subunit family
Database Links

HGNC: 7713

OMIM: 252010

KEGG: hsa:4726

STRING: 9606.ENSP00000274137

UniGene: Hs.408257

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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