NLGN3 Antibody, Biotin conjugated

1. Wnt/beta-catenin signaling targets the trasncription of the autism-associated Neuroligin 3 gene. PMID: 29503438
2. NLGN3 protects retinal pigment epithelium (RPE) cells and retinal ganglion cells (RGCs) from H2O2. PMID: 29792861
3. Our data suggest that these four previously described neuroligin mutations are not primary risk factors for autism. PMID: 28948087
4. high-grade gliomas growth depends on microenvironmental NLGN3, identify signalling cascades downstream of NLGN3 binding in glioma, and determine a therapeutically targetable mechanism of secretion PMID: 28959975
5. e found that NLGN3 function at inhibitory synapses in rat CA1 depends on the presence of NLGN2 and identified a domain in the extracellular region that accounted for this functional difference between NLGN2 and 3 specifically at inhibitory synapses. PMID: 27805570
6. No statistically significant haplotypes have been found associated to autism in the NLGN3 after logistic regression and permutation analysis. PMID: 27782075
7. The synaptic protein neuroligin-3 (NLGN3) was identified as the leading candidate mitogen, and soluble NLGN3 was sufficient and necessary to promote robust high-grade glioma cell proliferation. PMID: 25913192
8. Our data provided a further evidence for the involvement of NLGN3 and NLGN4X gene in the pathogenesis of autism in Chinese population. PMID: 24570023
9. The present study explores, for the first time, the contribution of NLGN3 and NLGN4X genetic variants in Greek patients with autistic disorder. PMID: 23851596
10. Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population. PMID: 23468870
11. Neuroligins are adhesion proteins that bind to beta-neurexin to form functional synapses. PMID: 23431752
12. Data from studies using cross-linking reagents suggest that neuroligins form dimers, including homodimers and, most notably, neuroligin 1/3 heteromers; autism-associated neuroligin mutant (neuroligin 3 R471C) forms heterodimers with neuroligin 1. PMID: 22671294
13. study provides initial evidence that a common variant in NLGN3 gene may play a role in the etiology of ASDs among affected males in Chinese Han population. PMID: 21569590
14. further characterization of the R451C mutation in NLGN3;role in protein folding PMID: 20227402
15. report mutations in two X-linked genes encoding neuroligins NLGN3 and NLGN4 in siblings with autism-spectrum disorders PMID: 12669065
16. No structural variants were found in the NLGN3 gene when 96 unrelated patients with autism, 24 ADHD and 24 bipolar disorder patients were analyzed. PMID: 15622415
17. Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
18. Data indicate that coding mutations in neuroligin 3 are very rarely associated to autism spectrum disorders. PMID: 16508939
19. Splice variants of the NLGN3 gene are associated with autism. PMID: 16648374
20. Syntrophin-gamma2 (SNTG2) is a de novo binding partner of neuroligin 3, which correlates with autism-related mutations. PMID: 17292328
21. no evidence for an involvement of NLGN3 and NLGN4X genetic variants with autism spectrum disorder on high functioning level PMID: 18189281
22. these data support the hypothesis that the autism-associated NL3 mutation affects information processing in neuronal networks by altering network architecture and synchrony PMID: 19406211

Show More

Hide All

HGNC: 14289

OMIM: 300336

KEGG: hsa:54413

STRING: 9606.ENSP00000351591

UniGene: Hs.438877