NP Antibody, FITC conjugated

Datasheet

Code	CSB-PA841983HC01RCI
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Reston ebolavirus NP Polyclonal antibody

Uniprot No.

Q91DE1

Target Names

Alternative Names

NP antibody; Nucleoprotein antibody; Nucleocapsid protein antibody; Protein N antibody; Reston NP antibody; rNP antibody

Raised in

Rabbit

Species Reactivity

Reston ebolavirus

Immunogen

Recombinant Reston ebolavirus Nucleoprotein protein (414-739AA)

Immunogen Species

Reston ebolavirus

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm. Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid. Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription. Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1.

Subcellular Location

Virion. Host cytoplasm.

Protein Families

Filoviruses nucleoprotein family

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