NPAP1 Antibody

Code CSB-PA284200
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA284200(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA284200(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
NPAP1
Alternative Names
NPAP1 antibody; C15orf2Nuclear pore-associated protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human NPAP1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in spermatogenesis.
Gene References into Functions
  1. NPAP1 is specific to primate species and absent from the 15q11q13-orthologous regions in all nonprimate mammals. PMID: 24482533
  2. C15orf2 is part of the nuclear pore complex or its associated molecular networks. PMID: 22694955
  3. C15orf2 gene is imprinted, with monoallelic expression from the paternal allele in fetal brain. PMID: 17337158
  4. These results indicate that C15orf2 might have an important role in human biology and that a deficiency of C15orf2 might contribute to Prader-Willi syndrome. PMID: 20020165
  5. The results from this study show an involvement of microdeletions at 15q11.2 that predispose patients to idiopathic generalized epilepsies. PMID: 19843651

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Subcellular Location
Nucleus, nucleoplasm. Nucleus inner membrane. Note=Colocalizes with the NPC and nuclear lamins at the nuclear periphery.
Tissue Specificity
Testis-specific in adults. In fetal brain expressed only from the paternal allele.
Database Links

HGNC: 1190

OMIM: 610922

KEGG: hsa:23742

STRING: 9606.ENSP00000333735

UniGene: Hs.649663

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