NR2C2AP Antibody, HRP conjugated

Code CSB-PA016053LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NR2C2AP Polyclonal antibody
Uniprot No.
Target Names
NR2C2AP
Alternative Names
nr2c2ap antibody; NR2CA_HUMAN antibody; Nuclear receptor 2C2 associated protein antibody; Nuclear receptor 2C2-associated protein antibody; Repressor for TR4 transactivation antibody; TR4 orphan receptor associated 16 kDa protein antibody; TR4 orphan receptor associated protein TRA16 antibody; TR4 orphan receptor-associated 16 kDa protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nuclear receptor 2C2-associated protein (7-139AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Gene References into Functions
  1. High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2 PMID: 23129017
  2. TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation PMID: 12486131
  3. Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells. PMID: 15381082
  4. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression. PMID: 17054912
Subcellular Location
Nucleus.
Protein Families
NR2C2AP family
Tissue Specificity
Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas.
Database Links

HGNC: 30763

OMIM: 608719

KEGG: hsa:126382

STRING: 9606.ENSP00000332823

UniGene: Hs.708153

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