NSUN5 Antibody, Biotin conjugated

Code CSB-PA839386LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NSUN5 Polyclonal antibody
Uniprot No.
Target Names
NSUN5
Alternative Names
FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; p120 antibody; Putative methyltransferase NSUN5 antibody; WBSCR20 antibody; WBSCR20A antibody; Williams Beuren syndrome chromosome region 20A antibody; Williams-Beuren syndrome chromosomal region 20A protein antibody; Williams-Beuren syndrome critical region protein 20 copy A antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable 28S rRNA (cytosine-C(5))-methyltransferase protein (362-466AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development.
Gene References into Functions
  1. Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome PMID: 11978965
Involvement in disease
NSUN5 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
Subcellular Location
Nucleus, nucleolus.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
Tissue Specificity
Ubiquitous. Detected in placenta, heart and skeletal muscle.
Database Links

HGNC: 16385

OMIM: 615732

KEGG: hsa:55695

STRING: 9606.ENSP00000309126

UniGene: Hs.510927

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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