NUP93 Antibody

Datasheet
Code CSB-PA822683LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q8N1F7
Image
  • IHC image of CSB-PA822683LA01HU diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Nuclear pore complex protein Nup93 protein (14-180AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93), NUP93, KIAA0095
Immunogen Species Human
Research Area Others
Target Names NUP93
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance
Involvement in disease Nephrotic syndrome 12 (NPHS12)
Subcellular Location Nucleus membrane, Peripheral membrane protein, Nucleus, nuclear pore complex, Nucleus envelope
Protein Families Nucleoporin interacting component (NIC) family
Database Links

HGNC: 28958

OMIM: 614351

KEGG: hsa:9688

STRING: 9606.ENSP00000310668

UniGene: Hs.276878

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