ORF1 Antibody

Code CSB-PA327230LA01HGE
Size US$166
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Product Details

Full Product Name
Rabbit anti-Hepatitis E virus genotype 1 (isolate Human/Pakistan/Sar-55) (HEV-1) ORF1 Polyclonal antibody
Uniprot No.
Target Names
ORF1
Alternative Names
ORF1 antibody; Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody; EC 2.1.1.- antibody; EC 2.7.7.-); Putative papain-like cysteine protease antibody; PLP antibody; EC 3.4.22.-); NTPase/helicase antibody; EC 3.6.4.-); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48)] antibody
Raised in
Rabbit
Species Reactivity
Hepatitis E virus genotype 1
Immunogen
Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)
Immunogen Species
Hepatitis E virus genotype 1 (isolate Human/Pakistan/Sar-55) (HEV-1)
Conjugate
Non-conjugated

The ORF1 Antibody (Product code: CSB-PA327230LA01HGE) is Non-conjugated. For ORF1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA327230LB01HGE ORF1 Antibody, HRP conjugated ELISA
FITC CSB-PA327230LC01HGE ORF1 Antibody, FITC conjugated
Biotin CSB-PA327230LD01HGE ORF1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Methyltransferase: Displays a capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m(7)GTP or m(7)GDP. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m(7)GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure.; Papain-like cysteine protease: May participate in the processing of polyprotein pORF1 together with cellular proteases and the cleavage of capsid protein ORF2.; NTPase/helicase: Multi-functional protein that exhibits NTPase and RNA unwinding activities. Hydrolyzes all NTPs efficiently and unwinds RNA duplexes containing 5' overhangs. Possesses a sequence independent RNA-5'-triphosphatase (RTPase) activity suggestive of its role in forming viral cap structure. Participates also in viral genome replication, RNA translocation and genome packaging/unpackaging.; RNA-directed RNA polymerase: Plays an essential role in the virus replication. Binds to the 3'-end of the genomic RNA to initiate viral replication.
Subcellular Location
Host cytoplasm.
Protein Families
Hepevirus non-structural polyprotein family
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