PGAP2 Antibody

Code CSB-PA883397LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA883397LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883397LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA883397LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PGAP2 Polyclonal antibody
Uniprot No.
Target Names
PGAP2
Alternative Names
PGAP2; FRAG1; Post-GPI attachment to proteins factor 2; FGF receptor-activating protein 1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Post-GPI attachment to proteins factor 2 protein (45-114AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PGAP2 Antibody (Product code: CSB-PA883397LA01HU) is Non-conjugated. For PGAP2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA883397LB01HU PGAP2 Antibody, HRP conjugated ELISA
FITC CSB-PA883397LC01HU PGAP2 Antibody, FITC conjugated
Biotin CSB-PA883397LD01HU PGAP2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
Gene References into Functions
  1. A Rare Variant in PGAP2 Causes Autosomal Recessive Hyperphosphatasia with Mental Retardation Syndrome, with a Mild Phenotype in Heterozygous Carriers. PMID: 29119105
  2. Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. PMID: 23561846
  3. PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. PMID: 23561847
Involvement in disease
Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3)
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
PGAP2 family
Tissue Specificity
Ubiquitously expressed, with highest levels in testis and pancreas.
Database Links

HGNC: 17893

OMIM: 614207

KEGG: hsa:27315

STRING: 9606.ENSP00000278243

UniGene: Hs.133968

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