PGLYRP4 Antibody, FITC conjugated

Datasheet

Code	CSB-PA017865LC01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PGLYRP4 Polyclonal antibody

Uniprot No.

Q96LB8

Target Names

PGLYRP4

Alternative Names

Peptidoglycan recognition protein 4 antibody; Peptidoglycan recognition protein I-beta antibody; Peptidoglycan recognition protein intermediate beta antibody; Pglyrp4 antibody; PGLYRPIbeta antibody; PGRP-I-beta antibody; PGRP4_HUMAN antibody; PGRPIB antibody; SBBI67 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Peptidoglycan recognition protein 4 protein (18-317AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.

Gene References into Functions

a significant induction of three PGLYRPs 2-4 in primary human corneal epithelial cells (HCECs) exposed to live or heat-killed Candida albicans, is reported. PMID: 26039076
This study demonistrated that PGLYRP4 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
Results describe the function of mammalian antimicrobial peptidoglycan recognition proteins 3 and 4, and show that they are a new class of bactericidal and bacteriostatic proteins. PMID: 16354652
Data are consistent with previous reports of association of psoriasis with genes on 1q21, and suggest a role for Pglyrp4 in skin biology. PMID: 16362825

Subcellular Location

Secreted.

Protein Families

N-acetylmuramoyl-L-alanine amidase 2 family

Tissue Specificity

Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongu

Database Links

HGNC: 30015

OMIM: 608198

KEGG: hsa:57115

STRING: 9606.ENSP00000352672

UniGene: Hs.58356

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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