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POF1B Antibody, FITC conjugated

Datasheet
Code CSB-PA840988LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) POF1B Polyclonal antibody
Uniprot No.
Q8WVV4
Target Names
POF1B
Alternative Names
2310066B14Rik antibody; FLJ22792 antibody; POF antibody; Pof1b antibody; POF1B_HUMAN antibody; POF2B antibody; Premature ovarian failure protein 1B antibody; Protein POF1B antibody; RGD1560798 antibody; RP1-75N13.2 antibody; RP23-336F13.1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein POF1B protein (532-589AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
Gene References into Functions
  1. POF1B was restricted to granular layers in human healthy epidermis, whereas it largely increased in hyperproliferative human skin diseases, thus demonstrating the localization of POF1B also in desmosomes of multistratified epithelia. PMID: 25084053
  2. The POF1B candidate gene for premature ovarian failure regulates epithelial polarity PMID: 21940798
  3. Our findings could not demonstrate any involvement of POF1B in premature ovarian failure PMID: 15459172
Involvement in disease
Premature ovarian failure 2B (POF2B)
Subcellular Location
Cell junction, tight junction.
Database Links

HGNC: 13711

OMIM: 300603

KEGG: hsa:79983

STRING: 9606.ENSP00000262753

UniGene: Hs.267038

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