PPP1R13L Antibody, Biotin conjugated

Datasheet
Code CSB-PA851965OD01HU
Size US$299
Uniprot No. Q8WUF5
Immunogen Peptide sequence from Human RelA-associated inhibitor protein (83-102AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein), PPP1R13L, IASPP NKIP1 PPP1R13BL RAI
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Cell Biology
Target Names PPP1R13L
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Subcellular Location Cytoplasm, Nucleus
Protein Families ASPP family
Tissue Specificity Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.
Database Links

HGNC: 18838

OMIM: 607463

KEGG: hsa:10848

STRING: 9606.ENSP00000354218

UniGene: Hs.466937

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