PSD4 Antibody

Datasheet

Code	CSB-PA843332LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA843332LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA843332LA01HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PSD4 Polyclonal antibody

Uniprot No.

Q8NDX1

Target Names

PSD4

Alternative Names

EFA6B antibody; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B antibody; FLJ36237 antibody; FLJ37279 antibody; PH and SEC7 domain-containing protein 4 antibody; Pleckstrin homology and SEC7 domain-containing protein 4 antibody; Ppleckstrin and Sec7 domain containing 4 antibody; PSD4 antibody; PSD4_HUMAN antibody; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein antibody; Telomeric of interleukin-1 cluster protein antibody; TIC antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PSD4 Antibody (Product code: CSB-PA843332LA01HU) is Non-conjugated. For PSD4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA843332LB01HU	PSD4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA843332LC01HU	PSD4 Antibody, FITC conjugated
Biotin	CSB-PA843332LD01HU	PSD4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

Gene References into Functions

results identify EFA6B as a novel antagonist in breast cancer and they point to its regulatory and signaling pathways as rational therapeutic targets in aggressive forms of this disease PMID: 25115298
One of the cytohesin family of guanine nucleotide exchange factors, Tic may act on the ARF family of GTP-binding proteins. A PH domain with similar sequence and relative position to those in other cytohesins may allow association with phosphoinositides. PMID: 11050434

Subcellular Location

Cell membrane. Cell projection, ruffle membrane.

Tissue Specificity

Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

Database Links

HGNC: 19096

OMIM: 614442

KEGG: hsa:23550

STRING: 9606.ENSP00000245796

UniGene: Hs.516306

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Related pathways

Endocytosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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