PSD4 Antibody

Datasheet

Code	CSB-PA843332LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA843332LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA843332LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PSD4 Polyclonal antibody

Uniprot No.

Q8NDX1

Target Names

PSD4

Alternative Names

EFA6B antibody; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B antibody; FLJ36237 antibody; FLJ37279 antibody; PH and SEC7 domain-containing protein 4 antibody; Pleckstrin homology and SEC7 domain-containing protein 4 antibody; Ppleckstrin and Sec7 domain containing 4 antibody; PSD4 antibody; PSD4_HUMAN antibody; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein antibody; Telomeric of interleukin-1 cluster protein antibody; TIC antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PSD4 Antibody (Product code: CSB-PA843332LA01HU) is Non-conjugated. For PSD4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA843332LB01HU	PSD4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA843332LC01HU	PSD4 Antibody, FITC conjugated
Biotin	CSB-PA843332LD01HU	PSD4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

Gene References into Functions

results identify EFA6B as a novel antagonist in breast cancer and they point to its regulatory and signaling pathways as rational therapeutic targets in aggressive forms of this disease PMID: 25115298
One of the cytohesin family of guanine nucleotide exchange factors, Tic may act on the ARF family of GTP-binding proteins. A PH domain with similar sequence and relative position to those in other cytohesins may allow association with phosphoinositides. PMID: 11050434

Subcellular Location

Cell membrane. Cell projection, ruffle membrane.

Tissue Specificity

Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

Database Links

HGNC: 19096

OMIM: 614442

KEGG: hsa:23550

STRING: 9606.ENSP00000245796

UniGene: Hs.516306

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Related pathways

Endocytosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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