PSMD5 Antibody

Code CSB-PA618074ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA618074ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA618074ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PSMD5 Polyclonal antibody
Uniprot No.
Target Names
PSMD5
Alternative Names
26S protease subunit S5 basic antibody; 26S proteasome non-ATPase regulatory subunit 5 antibody; 26S proteasome subunit S5B antibody; Protease 26S; subunit 5B antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase; 5 antibody; Proteasome 19S S5B antibody; Proteasome 26S subunit; non ATPase; 5 antibody; PSMD5 antibody; PSMD5_HUMAN antibody; S5B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 26S proteasome non-ATPase regulatory subunit 5 protein (255-504AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
Gene References into Functions
  1. the critical role of S5b/PSMD5 in negative regulation of proteasome by TNF-alpha/NFkappaB and provide insights into proteasome inhibition in human disease. PMID: 22921402
Protein Families
Proteasome subunit S5B/HSM3 family
Database Links

HGNC: 9563

OMIM: 604452

KEGG: hsa:5711

STRING: 9606.ENSP00000210313

UniGene: Hs.193725

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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