Phospholipase D LamSicTox-alphaIC1 Antibody

Code CSB-PA495649LA01LQU
Size US$166
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Product Details

Uniprot No.
Alternative Names
Dermonecrotic toxin LamSicTox-alphaIC1 antibody; EC 4.6.1.- antibody; Phospholipase D antibody; PLD antibody; Sphingomyelin phosphodiesterase D antibody; SMD antibody; SMase D antibody; Sphingomyelinase D antibody; Fragment antibody
Raised in
Rabbit
Species Reactivity
Loxosceles amazonica
Immunogen
Recombinant Loxosceles amazonica Phospholipase D LamSicTox-alphaIC1 protein (1-273AA)
Immunogen Species
Loxosceles amazonica (Recluse spider)
Conjugate
Non-conjugated

The Phospholipase D LamSicTox-alphaIC1 Antibody (Product code: CSB-PA495649LA01LQU) is Non-conjugated. For Phospholipase D LamSicTox-alphaIC1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA495649LB01LQU Phospholipase D LamSicTox-alphaIC1 Antibody, HRP conjugated ELISA
FITC CSB-PA495649LC01LQU Phospholipase D LamSicTox-alphaIC1 Antibody, FITC conjugated
Biotin CSB-PA495649LD01LQU Phospholipase D LamSicTox-alphaIC1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate. This toxin acts on sphingomyelin (SM). It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG). It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products. Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation.
Subcellular Location
Secreted.
Protein Families
Arthropod phospholipase D family, Class II subfamily
Tissue Specificity
Expressed by the venom gland.
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