QPRT Antibody, HRP conjugated

Datasheet

Code	CSB-PA621868LB01HU
Size	US$166
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) QPRT Polyclonal antibody

Uniprot No.

Q15274

Target Names

QPRT

Alternative Names

NADC_HUMAN antibody; Nicotinate nucleotide pyrophosphorylase (carboxylating) antibody; Nicotinate-nucleotide pyrophosphorylase [carboxylating] antibody; QAPRTase antibody; QPRT antibody; QPRTase antibody; Quinolinate phosphoribosyltransferase [decarboxylating] antibody; Quinolinate phosphoribosyltransferase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Nicotinate-nucleotide pyrophosphorylase [carboxylating] protein (113-254AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Involved in the catabolism of quinolinic acid (QA).

Gene References into Functions

Our data suggest that QPRT may play an important role in the pathogenesis of autism spectrum disorders in Chr16p11.2 deletion carriers. PMID: 30443311
WT1 knock-down gave a corresponding decrease in QPRT gene and protein expression. Chromatin-immunoprecipitation revealed WT1 binding to a conserved site in the first intron of the QPRT gene. PMID: 27889611
The structural features, size distribution, heat aggregation and ITC studies of the full-length enzyme and the enzyme lacking helix alpha1 strongly suggest that human QPRT acts as a hexamer for cooperative reactant binding via three dimeric subunits and maintaining stability. PMID: 26805589
Report of the crystal structure of human QPRT bound to its inhibitor phthalic acid (PHT) and kinetic analysis of PHT inhibition of human QPRT. PMID: 24038671
QPRT is a potential new marker for the immunohistochemical screening of follicular thyroid nodules. PMID: 19321014

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Protein Families

NadC/ModD family

Database Links

HGNC: 9755

OMIM: 606248

KEGG: hsa:23475

STRING: 9606.ENSP00000378782

UniGene: Hs.513484

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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