RAI1 Antibody, HRP conjugated

Code CSB-PA768772LB01HU
Size US$299
Uniprot No. Q7Z5J4
Protocols ELISA Protocol
Immunogen Recombinant Human Retinoic acid-induced protein 1 protein (617-823AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Retinoic acid-induced protein 1, RAI1, KIAA1820
Immunogen Species Homo sapiens (Human)
Research Area Neuroscience
Target Names RAI1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcriptional regulator of the circadian clock components
Involvement in disease Smith-Magenis syndrome (SMS)
Subcellular Location Cytoplasm, Nucleus
Tissue Specificity Expressed in all tissues examined with higher expression in the heart and brain. No expression was seen in the corpus callosum of the brain.
Database Links

HGNC: 9834

OMIM: 182290

KEGG: hsa:10743

STRING: 9606.ENSP00000323074

UniGene: Hs.655395

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