RALY Antibody, Biotin conjugated

Code CSB-PA892332LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RALY Polyclonal antibody
Uniprot No.
Target Names
RALY
Alternative Names
Autoantigen p542 antibody; Heterogeneous nuclear ribonucleoprotein C-like 2 antibody; hnRNP associated with lethal yellow protein homolog antibody; hnRNP core protein C-like 2 antibody; MGC117312 antibody; P542 antibody; RALY antibody; RALY_HUMAN antibody; RNA binding protein (autoantigenic hnRNP associated with lethal yellow) antibody; RNA binding protein (autoantigenic) antibody; RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)) antibody; RNA-binding protein Raly antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human RNA-binding protein Raly protein (254-306AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
Gene References into Functions
  1. hnRNP RALY regulates PMID: 28972179
  2. RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells PMID: 28733251
  3. RALY is a poly-U binding protein and as a regulator of H1FX and ANXA1 in mammalian cells. PMID: 28379492
  4. People with lower level of RALYL expression had a poorer survival rate. PMID: 22994768
Subcellular Location
Nucleus.
Protein Families
RRM HNRPC family, RALY subfamily
Tissue Specificity
Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
Database Links

HGNC: 15921

OMIM: 614663

KEGG: hsa:22913

STRING: 9606.ENSP00000246194

UniGene: Hs.136947

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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