RBM22 Antibody, FITC conjugated

Code CSB-PA889126LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RBM22 Polyclonal antibody
Uniprot No.
Target Names
RBM22
Alternative Names
Cwc2 antibody; FLJ10290 antibody; fSAP47 antibody; Functional spliceosome associated protein 47 antibody; Pre mRNA splicing factor RBM22 antibody; Pre-mRNA-splicing factor RBM22 antibody; RBM 22 antibody; rbm22 antibody; RBM22_HUMAN antibody; RNA binding motif protein 22 antibody; RNA-binding motif protein 22 antibody; ZC3H16 antibody; Zinc finger CCCH domain containing protein 16 antibody; Zinc finger CCCH domain-containing protein 16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pre-mRNA-splicing factor RBM22 protein (2-250AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
Gene References into Functions
  1. Cwc2/RBM22-RNA contacts are functionally important. PMID: 22246180
  2. ALG-2 alone evenly distributed within the cell, whereas in the presence of RBM22 the two proteins co-localized within the nucleus. PMID: 17045351
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
SLT11 family
Database Links

HGNC: 25503

OMIM: 612430

KEGG: hsa:55696

STRING: 9606.ENSP00000199814

UniGene: Hs.713564

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